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Transfusions are one of the most overused treatments in modern medicine, at a cost of billions of dollars. Researchers are working out how to cut back.

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Brain-scanning techniques promise to give an objective measure of whether someone is in pain, but researchers question whether they are reliable enough for the courtroom.

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   Information scientist Cassidy Sugimoto was initially sceptical that Twitter was anything more than a self-promotional time-sink. But when she noticed that her graduate students were receiving conference and co-authoring invitations through connections made on Twitter, she decided to give the social-media platform a try. An exchange that began last year as short posts, or 'tweets', relating to conference sessions led to a new contact offering to help her negotiate access to an internal data set from a large scientific society. “Because we started the conversation on Twitter, it allowed me to move the conversation into the physical world,” says Sugimoto, who studies how ideas are disseminated among scientists at Indiana University in Bloomington. “It's allowed me to open up new communities for discussions and increase the interdisciplinarity of my research.”

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    It seemed too good to be true, says Allard Mosk. It was 2007, and he was working with Ivo Vellekoop, a student in his group at the University of Twente in Enschede, the Netherlands, to shine a beam of visible light through a 'solid wall' — a glass slide covered with white paint — and then focus it on the other side. They did not have a particular application in mind. “I really just wanted to try this because it had never been done before,” Mosk says. And in truth, the two researchers did not expect to pick up much more than a faint blur.

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